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Amruthapala (Decalepis arayalpathra (J. Joseph and V. Chandras.) Venter): A Comprehensive Review on Diversity, Therapeutic Uses, and Valorization of Bioactive Constituents

[ Vol. 20 , Issue. 5 ]

Author(s):

Sonali Mishra, Nupur Srivastava, Velusamy Sundaresan and Karuna Shanker*   Pages 376 - 389 ( 14 )

Abstract:


Background: Decalepis arayalpathra (J. Joseph and V. Chandras.) Venter is used primarily for nutrition besides to its therapeutic values. Traditional preparations/formulations from its tuber used as a vitalizer and blood purifier drink. The folklore medicinal uses cover inflammation, cough, wound healing, antipyretic, digestive system management. A comprehensive review of the current understanding of the plant is required due to emerging concerns over its safety and efficacy.

Aim of the review: The systematic collection of the authentic information from different sources with the critical discussion is discussed and summarised in order to address various issues related to botanical identity, therapeutic medicinal, nutritional usage, phytochemical, and pharmacological potentials of the D. arayalpathra. Current use in traditional systems of medicine can be used to expand future research opportunities.

Materials and methods: Available scripted information was collected manually, from peered review research papers and international databases viz. Science Direct, Google Scholar, SciFinder, Scopus, etc. The unpublished resources which were not available in database collected through the classical books of ‘Ayurveda’ and ‘Siddha’ published in regional languages. The information from books, Ph.D. and MSc dissertations, conference papers and government reports were also collected. We thoroughly screened the scripted information of classical books, titles, abstracts, reports, and full-texts of the journals to establish the reliability of the content.

Results: Tuber bearing vanilla like signature flavour is due to the presence of 2-hydroxy-4-methoxy-benzaldehyde (HMB). Among five other species, Decalepis arayalpathra (DA) has come under the ‘critically endangered’ category, due to over-exploitation for traditional, therapeutic and cool drink use. The experimental studies proved that it possesses gastro-protective, anti-tumor, anti-inflammatory activities. Some efforts were also made to develop better therapeutic by logical modifications in 2-Hydroxy-4-methoxy-benzaldehyde, which is a major secondary metabolite of D. arayalpathra. ‘Amruthapala’ offers the enormous opportunity to develop herbal drink with health benefits like gastro-protective, anti-oxidant and anti-inflammatory actions.

Conclusions: The plant has the potential to generate the investigational new lead (IND) based on its major secondary metabolite i.e.2-Hydroxy-4-methoxy-benzaldehyde. The present mini-review summarizes the current knowledge on Decalepis arayalpathra, covering its phytochemical diversity, biological potentials, strategies for its conservation, and intellectual property rights (IPR) status.

Keywords:

Flavoured drink, functional potential, endangered species, Indian tribes, therapeutic action.

Affiliation:

Analytical Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow-226015, Analytical Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow-226015, CIMAP Research Centre, Allalasandra, GKVK Post, Bangalore-560065, Analytical Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow-226015



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